Research
Grigory Dianov
MRC Senior Group Leader
Our long-term goal is to study the proteins and mechanisms involved in the coordination and regulation of base excision repair, to unravel their role in the repair of radiation induced DNA damage and to examine the relationship to human diseases, such as cancer.
Ester Hammond
Cancer Research UK Junior Group Leader
The focus of my lab is the biological consequences of hypoxia initiating a DNA damage response in the absence of DNA damage.
Mark Hill
Investigate how differences in the biophysical features of radiation tracks determine biological response to evaluate impact on human health and facilitate radiation work across the Institute.
Tim Humphrey
MRC Senior Group Leader
Understanding how genome stability is maintained in response to DNA double-strand breaks.
Anne Kiltie
The focus of my lab is the investigation of DNA damage signalling and DNA repair as they relate to the aetiology of bladder cancer and its response to radiotherapy and combined modality treatments.
Tim S Maughan
Professor Maughan will lead the Clinical Research Programme at the Gray, aiming to deliver a step change in the effectiveness of radiotherapy through the evaluation of novel scientific approaches derived from the Institute's scientists in hypothesis driven clinical trials. In addition he aims to identify means to select patients for appropriate therapy through the use of functional imaging and biomarkers.
Gillies McKenna
Head of Department of Oncology and Director of Gray Institute for Radiation Oncology and Biology
The effects of radiation on cancer cells and on mechanisms of resistance to radiation with the goal of sensitizing cells to radiation by blocking mechanisms that control cell survival.
Ruth J Muschel
CRUK/MRC Professor of Molecular Pathology
Research group interested in the mechanisms underlying the development of metastasis.
Eric O’Neill
Cancer Research UK Junior Group Leader
The main areas of interest in our lab are cell signalling and stem cells and cancer stem-like cells.
Peter O'Neill
Group Head
Focuses on how clusters of DNA damage, formed by ionising radiation, detrimentally interfer with the maintenance of genome stability.
Anderson Ryan
Senior Group Leader
The focus of the group is to translate advances in our understanding of the molecular pathology of lung cancer and its microenvironment into better treatments for patients.
Madalena Tarsounas
CR-UK Senior Group Leader
How homologous recombination (HR), the major error-free pathway for DNA repair in mammalian cells, regulates telomeres and acts to prevent genomic instability, the underlying mechanism of many cancers.
Boris Vojnovic
CR-UK Senior Group Leader
Development of instrumentation to address specific biological hypotheses, primarily involving imaging and image processing.
